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Some people may not get the full benefit of tamoxifen. The body uses an enzyme called CYP2D6 to convert tamoxifen into its active form.
Until recently, most women who received adjuvant hormone therapy to reduce the chance of a breast cancer recurrence took tamoxifen every day for 5 years.
Information on the drug tamoxifen (Nolvadex) prescribed for the prevention and treatment of breast cancer. Side effects, drug interactions, and dosing information is provided.
Tamoxifen may cause cancer of the uterus (womb), strokes, and blood clots in the lungs. If you need to take tamoxifen to treat breast cancer, the benefits of tamoxifen outweigh the risks.
Tamoxifen is available in 10 mg and 20 mg tablets. When used for early-stage breast cancer, tamoxifen is usually prescribed at 20 mg a day for 5 years.
What is the most important information I should know about Tamoxifen? Do not use tamoxifen if you are pregnant. It could harm the unborn baby.
Tamoxifen is a medicine that blocks the effects of the estrogen hormone in the body. It is used to treat breast cancer in women or men.
Tamoxifen and raloxifene are drugs that can be taken to lower your risk of breast cancer. They belong to a class of drugs known as selective estrogen response modifiers (or SERMs).
Tamoxifen: A Major Medical Mistake? by Sherrill Sellman. Extracted from Nexus Magazine, Volume 5, #4 (June - July 1998).
Tamoxifen Back to top. Tamoxifen is an anti-oestrogen drug that was developed over 30 years ago. It is used widely to treat breast cancer and is occasionally used to treat some other cancers.
Tamoxifen has been linked to cause the following side effects: pulmonary embolism (blood clots in the lung) and cancer of the uterus (womb).
Tamoxifen is usually prescribed for women who are ER positive. That means that their breast cancer cells have oestrogen receptors (ER).
FA C T S F O R L I F E Tamoxifen Tamoxifen and breast cancer The drug tamoxifen Tamoxifen blocks the estrogen from binding to these receptors, preventing the breast cancer from growing.
In a recent study, precancerous uterine and endometrial changes were seen in 10% of the women taking tamoxifen. The higher the dose of tamoxifen, and the longer it is taken...
Synthetic hormone, used primarily in the prevention and treatment of breast cancer, that inhibits the growth-promoting actions of estrogen in breast cancer cells. Tamoxifen was first synthesized in 1962...

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